Mark Stenglein

Principal investigator
Google Scholar

I’m an Assistant Professor in the Microbiology, Immunology and Pathology department at Colorado State University. My research aims to apply a variety of old and new techniques to better understand viruses. I am motivated to do this because viruses can (sometimes) cause disease but also because I find them endlessly fascinating.


The expectations and challenges of wildlife disease research in the era of genomics: forecasting with a horizon scan-like exercise

Strengthening the Interaction of the Virology Community with the International Committee on Taxonomy of Viruses (ICTV) by Linking Virus Names and Their Abbreviations to Virus Species

A reverse-transcription/RNase H based protocol for depletion of mosquito ribosomal RNA facilitates viral intrahost evolution analysis, transcriptomics and pathogen discovery.

Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells.

Co-Infection Patterns in Individual Ixodes scapularis Ticks Reveal Associations between Viral, Eukaryotic and Bacterial Microorganisms

Adventitious viruses persistently infect three commonly used mosquito cell lines.

Xenosurveillance reflects traditional sampling techniques for the identification of human pathogens: A comparative study in West Africa

Divergent bornaviruses from Australian carpet pythons with neurological disease date the origin of extant Bornaviridae prior to the end-Cretaceous extinction.

Respiratory disease in ball pythons (Python regius) experimentally infected with ball python nidovirus

Metagenomic Investigation of Idiopathic Meningoencephalomyelitis in Dogs

Modeling the evolution of SIV sooty mangabey progenitor virus towards HIV-2 using humanized mice

Differential disease susceptibility in experimentally reptarenavirus infected boa constrictors and ball pythons

Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone

Detection and prevalence of boid inclusion body disease in collections of boas and pythons using immunological assays.

Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials

West African Anopheles gambiae mosquitoes harbor a taxonomically diverse virome including new insect-specific flaviviruses, mononegaviruses, and totiviruses

Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents

West Nile Virus Population Structure, Injury, and Interferon-Stimulated Gene Expression in the Brain From a Fatal Case of Encephalitis.

Age and prior blood feeding of Anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals.

Widespread Recombination, Reassortment, and Transmission of Unbalanced Compound Viral Genotypes in Natural Arenavirus Infections

Past, present, and future of arenavirus taxonomy

Genome Sequence of a Bornavirus Recovered from an African Garter Snake (Elapsoidea loveridgei).

Ball Python Nidovirus - a Candidate Etiologic Agent for Severe Respiratory Disease in Python regius.

Polar bear encephalitis - establishment of a comprehensive next-generation pathogen analysis pipeline for captive and free-living wildlife.

Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species.

A novel endogenous betaretrovirus group characterized from polar bears (Ursus maritimus) and giant pandas (Ailuropoda melanoleuca).

Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis.

Identification, characterization, and in vitro culture of highly divergent arenaviruses from boa constrictors and annulated tree boas - candidate etiological agents for snake inclusion body disease.

Virus identification in unknown tropical febrile illness cases using deep sequencing.

APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis.

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues - implications for HIV-1 restriction.

APOBEC3 proteins mediate the clearance of foreign DNA from human cells.

Two regions within the amino-terminal half of APOBEC3G cooperate to determine cytoplasmic localization.

The restriction of zoonotic PERV transmission by human APOBEC3G.

Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins.

APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.


Genomics of Disease in Wildlife Workshop, 2017

Shaun selected for a GAUSSI fellowship

New paper on mosquito viruses out

Rocky Mountain Virology Club

Goodbye, Joey!

Welcome, Jackie!

Lab hike in lieu of lab meeting

The lab is growing

Come join the fun!